Life-saving medicine One 700,000 in China, only 205 yuan abroad

 A special lifesaving drug Only A $41 is sold abroad (about RMB 205)Domestic sales of 700000?

 Recently, a media release of "medicine" information has attracted wide attention. Hunan a baby boy who has just turned 1 year old is lying in the hospital for more than 9 months because of a rare disease," spinal muscular atrophy (SMA)", which is in urgent need of special medicine to save a life, and the special drug Gnostic sodium injection needs 700000 yuan. This puts ordinary boy families on the verge of despair.

What kind of medicine is this? Why is the gap so big at home and abroad?

In order to find out the domestic pricing of Gnostic sodium, a mother of Guangdong, Ms. Ouyang, submitted an application to the State Drug Administration for disclosure of information such as the pricing of Gnostic sodium. Another lawyer has also applied to the State Drug Administration for disclosure of relevant pricing information, in response to the lawyer, the Chinese Drug Administration said that the pricing of the drug is not within the scope of acceptance of the National Drug Administration, proposed to apply to the National Development and Reform Commission for information disclosure, but also said that drug pricing is a market behavior

What kind of medicine is noxynasheng sodium injection?

 Gnostic sodium injection (Nusinersen) is the first approved SMA treatment drug in the world. As of June 30, 2020, Gnostic sodium injection has been approved in 50 countries and regions and has been reimbursed in more than 40 countries and regions.

 According to experts, Gnostic sodium injection is an antisense nucleotide therapy for type 5 q spinal muscular atrophy in infants, children and adults, and is also the first imported drug approved for the treatment of spinal muscular atrophy in China. Doctors use intrathecal injection (through the lumbar puncture to inject drugs into the body) to give patients medication.

 Children need to use drugs as soon as possible after diagnosis:6 times in the first year,4 injections in the first 2 months, and 1 injection every 4 months. Some children in injection after medication, exercise ability has a certain degree of recovery. A 2-year-old 11-month-old boy in Hunan province began injecting the drug in May and has been injected four times. After treatment, the motor ability of Nono was recovered well. "It's certainly useful in treatment, but it does n' t completely reverse the condition ."

Why is the drug so expensive?

 Gnostic sodium injection was approved for import in 2019 and is not currently included in health. In China, the price per unit of the drug is 699700 yuan.

 According to the newly revised drug management law in 2019, the drug price is no longer priced by the government but mainly regulated by the market, which plays a role through centralized bidding and procurement of medical insurance. Song Hualin, vice president of Nankai University Law School and expert in drug law, said that the number of patients with rare diseases is small and there is clinical uncertainty, so the cost of drug development is high and the price of drugs is expensive. Individual pharmaceutical enterprises often get pricing advantage because of technology leading, which does not necessarily violate China's anti-monopoly law or drug regulatory laws and regulations. He believes that the deep reason why rare diseases often attract attention is that the types of rare diseases that can be covered by medical insurance are limited, and commercial medical insurance in China still needs to be improved at the present stage, and the medical needs of patients with rare diseases are difficult to fully meet.

According to the staff of the Office of Letters and visits of the State Medical Insurance Bureau, Gnostic sodium injection has been included in the medical insurance negotiation schedule since its domestic listing in 2019, and the state hopes to negotiate with relevant pharmaceutical enterprises to reduce the price of drugs. And then meet the needs of SMA patients.

 Is the price of Chinese patients expected to decline? 

Last year, the country began negotiations with pharmaceutical companies, by the expert group to study pricing, the specific pricing is not clear. But the inclusion of health care has not been discussed, because drug prices do not come, there is always no way to enter the health care catalog.

 Why can't pharmaceutical companies be included in health care without falling prices? The staff of the Office of Letters and visits of the State Medical Insurance Bureau further explained to reporters that the medical insurance catalog developed by the State Medical Insurance Bureau is applicable to all parts of the country, so it is necessary to ensure that the drugs entered into the medical insurance catalog can be used everywhere. "Once such rare drugs are included in the health care catalog, for less developed regions, when the fund is used to pay for high-priced rare diseases, other underlying diseases may not be guaranteed, and subsequent local economic pressures may be created, so the most fundamental solution is for the state to negotiate with pharmaceutical companies and negotiate prices ."

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Trade situation in the United States and other countries

The latest data show that the U.S. trade deficit fell by $3.9 billion in May to $50.7 billion.

 Besides, what is the trade situation of China, Japan, Europe, Canada, Mexico and the United States —— the main trading partners of the United States?

On Wednesday, the Commerce Department released the latest June import and export data.

 Specifically, US exports in June amounted to $158.3 billion, an increase of $13.6 billion from May;

 In addition, US imports of $208.9 billion in June were $9.5 billion more than in May

 Finally, in June, the United States had a trade deficit of $50.7 billion, estimated at $50.2 billion; the trade deficit ——$54.6 billion in May fell by $3.9 billion.

After seeing the overall trade situation in the United States, let's look at the situation of the main trading partners of the United States-China and Japan!

 First of all, let's look at the trade data between the United States and China!

 In June, China again became the largest deficit country in the United States, with a $26.7 billion trade deficit with China in June, down $1.2 billion from $27.9 billion in May, according to figures released by the Commerce Department.

 In addition, the data showed that the U.S. trade deficit with Japan fell by $1.4 billion in June, to $1.8 billion.

 In June, U.S. exports to Japan increased by $200 million to $4.9 billion, while imports fell by $1.3 billion to $6.6 billion.

After reading the trade situation between the United States and China and Japan, let's take a look at the trade situation between the United States and other countries!

 In addition, the data showed that the U.S. trade deficit with Singapore fell by $1.4 billion to $200 million in June. Exports increased by $300 million to $2.1 billion and imports by $1.1 billion to $2.2 billion.

 Certainly, Wang said Caijing also noted that in June, the deficit of the United States and "old neighbors "—— Mexico increased by $4.8 billion, eventually reaching $9 billion.

 According to specific import and export data, Mexico's exports to the United States increased by $4.8 billion to $15.5 billion in June and imports by $9.6 billion to $24.5 billion.

 Actually, Wang Ye said that finance also noticed, June, The largest trade deficit in the United States is China ($26.7 billion), the European Union ($13.1 billion), Mexico ($9 billion), Germany ($3.8 billion), Italy ($2.1 billion), South Korea ($1.9 billion), India ($1.7 billion), France ($1 billion), Saudi Arabia ($700 million), Singapore ($200 million) and Canada ($100 million).

 Of course, in June, the United States also had some surplus countries.

 Specifically, in June, the United States had a surplus of $1.8 billion for South and Central American countries, the United Kingdom ($1.3 billion), OPEC ($500 million) and Brazil ($400 million).

 Our plastic injection molding industry, the main customers are also from the United States. this year to now, we clearly feel the decline in orders, so the United States trade deficit reduction we can feel.

1.4 billion Chinese are less able to consume than 330 million Americans

  "There is food in the hand, not panic in the heart ", the Chinese love to save money, in the world is very famous. As the country with the highest savings rate, our people have also been the savings market "frequent customers ". And even if we have money, we also find that many people dare not "consume ". Why is it that the US, with a population of 330 million, has become the world's second-largest consumer of 1.4 billion Chinese? After the study, we found that the deposit had been emptied —— the house.

   Even in small cities with three or four lines, the unit price of the house has reached five figures. At the same time, what is our income situation? Even in the more economically developed east, the average annual wage is only about 68000 yuan, with an average monthly income of 5600 yuan. In front of ten thousand yuan house prices, dare not spend money seems to be very reasonable.

    For most Chinese families, there is a house to have a home. In order to buy a house of their own, two or three generations of people's "empty" savings, has long been used to. Suppose the unit price per square meter is 20,000 yuan or 100 square meters of the house needs 2 million, how many families can take out 2 million at one time? Loans to buy houses has become the majority of ordinary Chinese families "only way ".

   In addition to the down payment of 600000, but also to the bank loan 1.4 million. Assuming that the loan term is 30 years, according to a certain interest rate, double repayment is not a word. Suppose the current interest rate is 5.65, then the monthly mortgage is about 8000 yuan. Such mortgage payments, so that many people in spending become "afraid of the hands and feet ". Not only that, but many families also need two generations to earn money to ease monthly mortgage pressure. And this is only "empty house" price, as well as decoration fees, property management fees and so on.

   When you need to pay 8000 yuan a month, even if you earn 10000 yuan a month, I am afraid you dare not wantonly spend. In addition to the house, we still have a lot of investment in life, such as medical care, pension, and so on. And people live in the world, often not alone. For many families, they also need to support the elderly and raise children. The existence of these relationships is a large sum of money. At this point, we also found that more and more people dare not marry, dare not have children. High house prices not only "empty" savings, but also become an effective "pill ".

   In the sixth census, We've found a growing population of 60 and over 65, And newborns are constantly decreasing. Take the post-90s, The total is only 175 million. And less after 00, Only 146 million people remain. Compared to the post-90s, Less than 33. The post-90s and post-00s compare more than 200 million people in the post-70s and post-80s, The contrast results are obvious. Even if we liberalize the "second-child policy ", There are still many couples who don't want to have children, High house prices have become one of the main reasons.

 Coupled with the fact that people now understand the importance of "cash flow" after 2020. In this environment, more and more Chinese families dare not consume. Buy a house, almost "empty" all the wealth, and then consider education, medical care, pension and so on, naturally want to spend also dare not spend.

   CNMOULDING think, an invisible pressure so that they become more powerful, do you agree?

Non-standard employment trends for mainstream college graduates

 In 2020, the number of graduates of ordinary colleges and universities reached 8.74 million, a record high. At the same time, under the influence of the global epidemic situation of new crown pneumonia and the change of international situation, the downward pressure of the economy is great, which makes it more difficult for college graduates to obtain employment. To solve the employment problem of college graduates, on the one hand, we need to strengthen our work, the Party and the government attach great importance to this," steady employment "and" guaranteed employment "has been listed as the first party and government work; on the other hand, college graduates need to understand the changing job market, change their mentality before new employment trends such as non-standard employment and informal employment, meet the challenges, and start their first job in their careers with a positive attitude.

Non-standard employment is the trend

At present, there is no strict consensus definition of what is non-standard employment (Non-standard employment), whether in academic or official. Generally speaking, non-standard employment refers to work outside the scope of the standard employment relationship. The standard employment relationship refers to full-time, indefinite, and part of the subordinate employment relationship. In some cases, researchers also define standard employment relationships as work performed outside the home. When this definition is adopted, more tasks are classified as non-standard employment, including e-office and other forms of telecommuting. In November 2016, the International Labour Organization released the World's Non-standard Employment: Understanding Challenges, Shaping the Future report (hereinafter referred to as the report), which divides non-standard employment into four types: temporary employment; part-time work; temporary agency work and other multi-employment relationships; covert employment and dependent self-employment. The statistics in the Report show that in the past few decades, both developed and developing countries have experienced a dramatic shift from standard to non-standard employment, and that non-standard employment is becoming universal throughout the world.

Non-standard employment of college graduates is on the rise

 Since China's reform and opening up, there have been many new changes in the employment mode in the labor market, and the proportion of flexible employment belonging to non-standard employment has increased significantly. In June 2004, for the first time, the Ministry of Education included flexible employment, including self-employment and free occupation, in the revised Statistical Approach to the Employment of Graduates. On June 29,2020, the General Office of the Ministry of Education issued the circular of the General Office of the Ministry of Education on strictly verifying the employment data of college graduates of the 2020 session, which further clarified the meaning of the relevant indicators of employment statistics for college graduates. Among them, the bright spot lies in "independent entrepreneurship" and "freelance ", the scope of independent entrepreneurship has joined the opening of online stores, the scope of freelance has joined the Internet marketing workers, public number bloggers, e-sports workers and so on.

 So, what is the non-standard employment situation of college graduates in China? Since 2003, the Institute of Education Economics of Peking University School of Education has conducted a national survey on the employment situation of college graduates every other year. So far, nine times have been carried out. Through the statistical analysis of the survey data, we find that the non-standard employment of college graduates presents the following characteristics:

 First, the proportion of non-standard employment is significant. In the direction of college graduates, There are four cases of employment, Where "identified units" can be classified as standard employment, "Self-employment "," freelance" and "other flexible employment" can be classified as non-standard employment. The proportion of non-standard employment shows an overall upward trend, The average of the nine surveys was 23.5 percent, The average of the last seven surveys was 27.9 percent, The average of the last five surveys was 29.1 percent, The average of the last three surveys was 33.9. Visible, Non-standard employment has become an integral part of college graduates' employment.

  Second, the proportion of active choice of non-standard employment is large. The National Survey of College Graduates Employment (2019) released by Peking University shows that graduates choose non-standard employment more actively. 62.5 percent of graduates considered non-standard employment "free time" and 55.9 percent considered "flexible working methods ". The reasons for graduates' passive choice of non-standard employment are "the wages of the work unit are too low "(20.0%)," not interested in the work of the unit "(18.5%)," not employed by the desired unit "(14.1%)," the development prospect of the work unit is not good enough "(11.8%).

 Third, there are significant educational differences in non-standard employment. In the 2019 Survey, non-standard employment (self-employment, freelance and other flexible employment) accounted for 21.9 percent,11.7 percent,7.2 percent and 6.6 percent of graduates, respectively. The higher the level of education, the lower the proportion of non-standard employment; among graduates,31.5 percent,28.2 percent,11.2 percent and 11.1 percent of graduates chose non-standard employment.

 As far as the current employment situation is concerned, there is still a big gap between the overall education level of our labor force and the developed countries, and the educational structure of the labor force is slightly weak in supporting the upgrading of the industrial structure. It is suggested that the following aspects should be studied: first, for college graduates, the problem of educational mismatch in student employment can be explained from the perspective of the urban structure of student employment; second, the matching of graduates' professional structure and labor market occupational structure needs to be discussed in more detail

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China's current demographic dividend has shifted from cheap workers to expensive pensions

 China's manufacturing industry has created one miracle after another in the past few decades, which is inextricably linked to China's demographic dividend

 Once made in China was an important support for China's economic development, and now Southeast Asian countries are beginning to make efforts in the middle and low-end manufacturing industries. And by China's family planning, labor force comprehensive quality improvement and other factors, China's demographic dividend advantage is gradually losing.

 Uniqlo, Nike, Foxconn, Samsung and other world-renowned companies have opened new factories in Southeast Asia and India, moving out of China. In recent years, Dongguan, known as the manufacturing capital, has closed hundreds of large factories.

But do you think the demographic dividend is over? The second demographic dividend

 When a country or region accounts for 10% of the population over 60 years old or 7% of the population over 65 years old, it means that the population of this country or region is in an aging society.

 At present, Japan is the world's most aging population, the proportion of people over 65 years old reached 27%, ranked first in the world, while Italy 23%, Germany 21% ranked second and third.

 2019 global population aging problem intensified, China's population aging growth rate of the world's first!

 For today's China, the population base is large, the economic development is also advancing by leaps and bounds, but the per capita proportion is small, also faces the population age question, has become the economic development a resistance.

It is expected that by 2030, China's population over 65 years of age will exceed that of Japan, becoming the world's most aging country. In 2050, society will enter the stage of deep aging.

 With the acceleration of the aging process, the resources of nursing homes in China are gradually in short supply. Many investors have seen business opportunities in nursing homes.

 Now the pace of urban life is relatively fast, young people's work is busy, life pressure is great, there are many people do not have time and energy to take care of the elderly at home, so choose to send the elderly to nursing homes, I hope the elderly can get more professional care.

 Now the general nursing home charge is basically made up of nursing fee, accommodation fee, board fee, basic medical reserve fee, and so on several aspects, comprehensive these items, the ordinary nursing home charge is about 5000 yuan per month, of course, the cost will also be local standard, and the actual situation of the elderly have a certain relationship.

 Some mobility inconvenience, life can not take care of the elderly, fees can reach about 10,000 yuan if a nursing home can recruit 30 people, then a year, nursing home investment costs can be earned back.

The Economic Reference has published an article entitled "Pension, education, medical care is expected to stimulate domestic demand" troika "article. At present, the rigid demand in the fields of old-age care, education and health care is explosive

 In the first-tier cities, it is understood that the phenomenon of "one bed is difficult to obtain" in nursing homes is more common, and the contradiction between the demand for a blowout and the shortage of supply is becoming increasingly sharp.

 "Behind the big problem is the big opportunity, as long as the measure is appropriate, the endowment will become the new motive force of economic development quickly ." Zhang Kai, vice president of the China Association of Aging Industry, said.

 As a pioneer in the pension industry for more than 10 years, Hunan "Chinese Care" Company CEO Longpan believes that the pension industry is likely to become the next industry after the real estate "rich mine ".

 Zhao Baoquan, president of Happy Old People's Daily, believes that the "middle class" consumption capacity of the first cities that are aging is relatively strong, and the consumption will is strong, and they are eager to enjoy professional pension services.